The “Baby Fae” baboon heart transplant—Potential cause of rejection
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چکیده
منابع مشابه
Baby Fae: a beastly business.
The Baby Fae experiment has highlighted the growing trend in medicine of using animal parts in the treatment of humans. This paper raises the question of the logical and moral justification for these current practices and their proposed expansion. We argue that the Cognitive Capacity Principle establishes morally justified necessary and sufficient conditions for the use of non-human animals in ...
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Long-term success in xenotransplantation is currently hampered by acute vascular rejection. The inciting cause of acute vascular rejection is not yet known; however, a variety of observations suggest that the humoral immune response of the recipient against the donor may be involved in the pathogenesis of this process. Using a pig-to-baboon heterotopic cardiac transplant model, we examined the ...
متن کاملNK cell depletion delays corneal allograft rejection in baby rats
PURPOSE Penetrating keratoplasty has a very poor outcome compared with adults if performed in the first years of life. Rejection in these young patients occurs even in the absence of known immunological risk factors. Recently, a baby rat model was introduced and an essential contribution of natural killer (NK) cells during allograft rejection was suggested. To analyze this, NK cells were deplet...
متن کاملDo we need the term "FAE"?
ABBREVIATIONS. FAS, fetal alcohol syndrome; FAE, fetal alcohol effect. Fetal alcohol syndrome (FAS) was first recognized as a distinct clinical entity by Jones and Smith in 1973.' In their first reports, 2,3 all affected children had been born to severely alcoholic women, and had in common problems in three major categories: 1. prenatal and/or postnatal growth deficiency; 2. abnormal brain func...
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ژورنال
عنوان ژورنال: Xenotransplantation
سال: 2019
ISSN: 0908-665X,1399-3089
DOI: 10.1111/xen.12511